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Buprenorphine's pharmacologic profile is well suited for medication assisted treatment (MAT) in opioid dependence.
This pharmacologic profile suggests that mapatumumab may have therapeutic benefit in the treatment of NSCLC.
Background: Etizolam is an anxiolytic drug with a pharmacologic profile similar to that of the classic benzodiazepines.
The pharmacologic profile of OnabotulinumtoxinA makes it an appealing candidate for CM patients.
The pharmacologic profile of onabotulinumtoxinA makes it an appealing candidate for CM patient's profile.
Neither DEX nor CCD altered the cell viability, gene expression, or pharmacologic profile of ATP-release pathways.
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The identified relationships between efficacy, clearance, and lipohilicity may help guide development of new camptothecin analogs and delivery systems with improved pharmacologic profiles.
In this study, four points of diversity within a dibenzo-epine scaffold were varied systematically and the pharmacologic profiles of the compounds were assessed across 14 receptors and transporters thought to be important to clinical profiles of efficacy and safety.
Cell volume was monitored by electronic cell sorting.Hypotonicity (50%) and mechanical stretch increased ATP release with similar pharmacologic profiles.
While the current H1N1 influenza (flu) pandemic was ongoing in 2010, efforts were made to develop new antiviral agents for influenza treatment that possess an improved spectrum of activity or better pharmacologic profiles, compared to current treatments.
Overall, preclinical data support the concept that TSECs exhibit distinct pharmacologic profiles.
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