Sentence examples for pharmacodynamic effect from inspiring English sources

These changes resulted in enhanced oral bioavailability and a superior pharmacodynamic effect in vivo.

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials.

OAA/S scores and bispectral index values, as surrogate measures of pharmacodynamic effect, were not different during this time in either trial.

On-target side effects refer to the pharmacodynamic effect on normal tissues, and off-target side effects are unexpected toxicities derived from the inhibition of unintended or unknown functions36.

To evaluate the safety and pharmacodynamic effect of co-administration of subtherapeutic doses of PT-141, a cyclic heptapeptide melanocortin analogue, and sildenafil to patients with erectile dysfunction.

Although on theoretical grounds monitoring the pharmacodynamic effect makes more sense than monitoring drug concentrations, in daily practice pharmacodynamic monitoring is not performed.

AIMS CYP3A4-metabolized stAIMS CYP3A4-metabolized pharmacodynamic effect of clopidogrel.

Model parameters included potency and rate constants for loss of pharmacodynamic effect by hydrolysis dependent and independent processes.

The relevance here is that the combined pharmacodynamic effect of alcohol and opioids may be even more enhanced by AIDD.

RESULTS: The predicted pharmacodynamic effect of TPZ was increased with fluctuating (vs. constant) hypoxia at all frequencies (1-30 min period) and all amplitudes (1-15 mm Hg).

Non vitamin K oral anticoagulants (NOACs) do not require regular monitoring but information about their pharmacodynamic effect may be importantin situations like trauma, stroke oremergent surgery.