Exact(2)
Delivery systems for proteins and genes have taken more than 25 years to emerge as a feasible pharmaceutical tool and several therapeutic proteins and genes are marketed already (Table 1).
Owing to the unique effects of MMRi64 on the critical components of the p53 regulatory loop and downstream effectors, MMRi64 may be used as a pharmaceutical tool to dissect the molecular regulation of p53-dependent transactivation program.
Similar(58)
They'll also use genetic and pharmaceutical tools to manipulate astrocyte activity.
Continued translational research resulted in better understanding of diabetes, which, in combination with cutting-edge biology, chemistry, and pharmaceutical tools, have allowed for the development of safer, more effective and convenient insulins and GLP-1.
The importance of a synthesized lysine-based gemini surfactant (labelled C6 LL 2) was evaluated in drug delivery by designing cationic niosomes as usable pharmaceutical tools of chemotherapeutics and antibiotics, respectively like methotrexate and tetracycline.
This process for obtaining antibacterial surfaces can be used for different applications in a wide range of fields like in buildings, pharmaceutical tools, and other instrumental devices.
The identification of quercetin as an agent that targets CSPα is a first step in the identification of pharmaceuticals that target members of the large J protein family and as such serves as proof of principle that pharmaceutical tools can selectively target J proteins.
Accordingly, aromatase inhibitors are currently established as good pharmaceutical tools for the treatment of ER-positive breast cancers.
They are composed of a head-to-tail cyclized backbone and a cystine-knot motif, which confers them with remarkable stability, thus making them attractive pharmaceutical tools.
In order to define the efficacy of these pharmaceutical tools in MADA cells, we considered the labelling pattern of tri-H3K9 as a parameter, and monitored its staining before and after drug treatment.
These aspects need to be taken into account for the development of new therapeutic protocols that could exploit the combined usage of canonical chemotherapy with novel pharmaceutical tools targeting the adaptive splicing response associated with treatments.
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