Exact(1)
This observation suggests that sequence-based PsePSSM features that reflect the effect of sequence order carry almost no complementary information with other PFs extracted from the PSSM profile (PS1, PS2, PS3 and PSp0).
Similar(59)
PF extracted data from the Central Cattle Database.
ROC curve analysis revealed that for improved patients the AUC was 0.76 (95% CI: 0.49 - 1.00) for the LEFS, 0.71 (95% CI: 0.45 - 0.98) for the WOMAC-PF (extracted from the HOOS-PF and KOOS-PF) and 0.68 (0.44 - 0.93) for the SF36-PF.
We studied the responsiveness of the LEFS and the WOMAC-PF extracted from the HOOS-PF and KOOS-PF) in a combined hip and knee group, as only a very small number of patients reported clinically important change, thus not allowing to study the responsiveness of the HOOS and KOOS separately.
However, prior administration of the PF extract showed significant protection against bromobenzene induced renal damage by reversing all above parameters.
Mitochondrial dysfunction induced by bromobenzene was protected much better with the PF extract than with vitamin E. These results suggested that the Phyllanthus fraternus extract is an efficient armament against nephrotoxicity induced by bromobenzene.
Male Wistar rats divided into six (A-F) groups and the experimental animals were administered bromobenzene with or without prior administration of PF extract or vitamin E. Animals were sacrificed and the kidneys obtained for studying mitochondrial function and histopathology.
Therefore, it was concluded that the dose up to 2000 mg/kg of the PF extract was safe for the use.
The histopathology of STZ induce diabetic rats, as expected the test dose of PF extract considerably modulates the pathological condition of various vital organ viz.
Oral administration of different doses of PF extract and glibenclamide significantly decline (P < 0.001) the rise in blood glucose levels, after glucose administration.
The consequence of the acute effect of graded doses of PF extract on blood sugar level of normal healthy rats and glucose loaded were presented in the Figure 3.
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