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In line with the methodology of PETs, we defined outcome in our daily practice population as the extent of improvement on the MADRS (difference between baseline and post treatment), and in line with the methodology of both AETs and PETs also as proportion of responders (50% reduction of symptoms), and as proportion of remitters (MADRS ≤10) [ 20] after the first step treatment for MDD.
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In addition to the SUV criterion defined by the EORTC PET study group, we defined a partial response as a decrease in the number of visible lesions with or without a decrease in FDG uptake or a decrease in FDG uptake with or without a reduction in the number of lesions.
In Jack et al. (2014 b ) we defined A+ by amyloid PET and defined N+ as either abnormal head-size-adjusted hippocampal volume or abnormal fluorodeoxyglucose (FDG) PET, a definition of N+ consistent with the NIA-AA criteria.
Based on the mid-therapy and post-therapy PET/CT results, we defined ∆SUVmax of 25%, 50%, and 75% as cutoff points.
"I'm still a bit wary about this article, to be honest!" This image problem, Sean believes, comes down to a fundamental question that is too often neglected: How do we define the word pet?
PETs have defined the context of Privacy by Design (PbD), as the promotion of consumer privacy within organizations is important at every stage of product/service development [30].
PETs are defined as privacy-enhancing technologies that attempt to reduce privacy risks, minimize data held on individuals, and empower individuals to control their own data [32].
In Table 2, we present the baseline features and symptom outcome in ROM patients suffering from MDD. Caption: Within Group Effectsize is a definition of treatment outcome often used in PETs and defined as: the extent of improvement (Δ MADRS pre- and post treatment within the group under investigation) adjusted for the standard deviation pre treatment.
Patients were also classified into subgroups of those undergoing a PET study within (defined as early PET study) or later than (defined as late PET study) 3 months after the last ischemic event.
In the literature, the baseline severity threshold (a cut-off score of 14 on the HAM-D-17 for PETs) is usually defined as a score on the HAM-D-17.
VOIs of 67 focal MS lesions visible in PET were defined on SUVR images.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com