Importantly, these estimates likely underestimate the true risk of progression to myeloma as they exclude patients with presumably higher grade lesions on PET-CT who were initiated on therapy based solely on the PET-CT finding (n=12 in this cohort).
Using echocardiography and FDG PET, the main finding of this study was that diabetic cardiomyopathy in an experimental model of diabetes is characterised by RV and LV alterations.
When lymph nodes were positive for malignancy by EBUS-TBNA irrespective of PET findings (PET-positive, n = 19; PET-negative, n = 3), the predictive value of EBUS-TBNA for lymph nodes diagnosis was 100% (Fig. 1).
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Thoracic pathology findings to be used for comparison with 99mTc-EC-DG and F-FDG PET scan findings in this study were reviewed by a single physician certified by the American Board of Pathology.
Hence, this may lead to a false-positive PET finding.
There was a false-positive PET finding in 1 patient and a false-negative PET finding in another patient.
A positive 18F-FDG PET finding in both cardiac and extra-cardiac regions is not specific to sarcoidosis.
The single false-positive PET finding corresponded to a histolopathological diagnosis of follicular hyperplasia.
These PET findings support this interpretation, that is 5-HT availability is decreased in the raphe-cortical serotonergic pathway.
