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Prior to the availability of CT and PET, management of a SPN could be watchful waiting or immediate biopsy.
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Our analysis suggests the involvement of other factors not included in the model like humidity, population distribution, knowledge of and interest in the disease by the scientific community, and probably pets management (there is a huge stray dogs population lacking preventive measures in the former USSR acting as reservoirs), among others.
Therefore, PET waste management with upcycling concept has become an important social issue because of PET's increasing consumption and non-biodegradability.
All of the patients were previously reported in a study evaluating how 68Ga-PSMA-11 PET changed management in patients with BCR [12].
PET changed management in 14% of cases [ 15].
PET changed management in 16% (10 out of 61) of cases.
Whole body FDG PET alters management in up to 40% of cases.
This study demonstrated that PET changed management in 34% and was best on discordant results (compared with conventional imaging) with an accuracy of 95% (p<0.0001).
Similarly, although again not validated in individual patients, the scale of the clinical impact of PET on management in various cancers has been demonstrated by prospective studies in the United States as part of the National Oncologic PET Registry NOPRR).
The positive impact of FDG-PET on management decisions in this clinical scenario is evident.
The impact of FDG-PET on management of patients with a rising serum CEA after primary curative treatment has also been examined [ 47, 55, 56].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com