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However, the high sugar content of the very high gravity fermentation medium causes an increase in the osmotic pressure, which has a pessimistic effect on yeast cells, and the fermentations are rarely fast and complete.
These findings indicate that SOX4-related chemoradioresistance has a pessimistic effect on survival in patients with OSCC.
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Afterward, process and project datasets (e.g., with optimistic and pessimistic effects, including the processes of one or several departments) can be combined to scenarios (Fig. 3 on the right).
Contrary to many pessimistic predictions regarding the effect on letter writing of modern means of communication, such as the telephone, together with an apparently increasing penchant for haste, some of the richest, most revealing, and most thoughtful letters of all times were written in the 20th century; those of the English writers Katherine Mansfield and D.H. Lawrence are paramount among them.
I've been pessimistic about the Apple Watch's effect on health care for more than six months, ever since it became clear that the hype over Apple was outpacing reality.
The slaughter in the trenches of the First World War, had a profound effect on Welsh literature with a more pessimistic style of prose championed by T. H. Parry-Williams and R. Williams Parry.
To have a significant effect on asset prices, they need to borrow from traders with pessimistic beliefs using loans collateralized by the asset itself.
But to do more substantial damage, rising interest rates would have to have a big effect on earnings themselves.Some equity analysts are already growing more pessimistic.
His argument is so obviously blind to reality, pessimistic about public services and patronising to working people that I described it as "utter balderdash", or words to that effect, on radio the other day.
The increase, of 13 million Americans, was much larger than even the most pessimistic observers of hunger trends had expected and cast an alarming light on the daily hardships caused by the recession's punishing effect on jobs and wages.
"We know from countless studies in psychology and neurology that your current emotional state has a huge effect on the quality of your work and when you're feeling blue you are less productive, less motivated, more pessimistic, less creative, less engaged and learn more slowly–just to mention a few effects," Kjerulf says.
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