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Synthetic phenotype VSM growth and hyperplasia are hallmarks of pervasive vascular diseases including hypertension, atherosclerosis, postangioplasty/in-stent restenosis, and vein graft failure.
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Extensive data from the literature indicate that autonomic nervous system dysfunction intrinsic to schizophrenia and strongly exacerbated by antipsychotic treatment is the cause of the pervasive metabolic and vascular dysfunctions associated with schizophrenia.
Endothelial activation also plays a pervasive role in atherosclerosis, a chronic vascular inflammatory disorder that is characterized by vessel narrowing, thrombosis and occlusion (Gimbrone & Garcia-Cardena, 2012; Pober & Sessa, 2007).
Thus, the elucidation of the miR-210-ISCU1/2-Fe-S axis expands the pervasive relevance of mitochondrial dysfunction in additional vascular cell types beyond muscle tissue in PH and emphasizes the therapeutic potential of targeting this metabolic pathway in vascular endothelium.
11 Overall, those data demonstrated that, along with peripheral vascular occlusive disease, accelerated vascular stiffening is an early and pervasive mechanism of vascular disease in HGPS.
Corruption was pervasive.
Substance abuse is pervasive.
Government corruption is pervasive.
It was very pervasive.
Uncertainty is pervasive.
Intelligence police are pervasive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com