Although this freshwater fauna is relatively depauperate additional taxa need to be studied to determine if this is a pervasive observation in freshwater systems of Chile and how ecological interactions are currently operating on the entire species assemblage.
As disulfide exchange between PDI family members is pervasive, these observations suggest that a more reduced ER poise would favor re-uptake of calcium into the ER and disfavor its release.
While pervasive, this observation has rarely been seriously examined.
"The situation is very different for the oceans," Dr. Knowlton and Dr. Jackson wrote, because degradation of ocean ecosystems is so pervasive, and underwater observation is relatively recent.
But their influence on the American scene is more pervasive than that observation suggests.
The observation of pervasive somatic and lethal mosaicism in crosses of F1 master females to wild-type males raised the possibility that maternally inherited Cas9 gRNA complexes in F2 ♀ might also persist and act in the germline to generate some degree of gene-drive or allelic-drive in the F3 generation, even in animals that did not inherit the Cas9 transgene.
This observation supports pervasive ongoing positive selection through 40,000 generations in these experimental populations (Barrick et al. 2009).
A significant application of this theoretical model exists in the observation of pervasive whole-cell adaptations in selected ion channels (I Na, I CaL) after cocaine sensitization, with implications of the type of learning that underlies addiction.
On the basis of our observation of pervasive backbone motions on the microsecond time scale in human DHFR, it seems highly likely that catalytically relevant motions in the human enzyme are much faster than in E. coli DHFR.
Particularly for ChIP-Seq studies, our observations of the pervasive inhomogeneity of coverage in the input sample highlighted the need to normalize the sequence read counts from ChIP samples to the input control counts.
Whether people are animated by guilt, observation of blacks' pervasive disadvantages, or the racially stratified nature of almost all of our institutions, they would have to be mad or willfully blind not to be racialist -- and callous not to sympathize with the plight of blacks and other subordinated groups.
