Sentence examples for perturbed regulation from inspiring English sources

Perturbed regulation of both proliferation and apoptosis, severity of gastric atrophy, and dysplasia are implicated in the susceptibility to gastric cancer.

A plausible hypothesis for progression of benign steatosis to steatohepatitis is the perturbed regulation of inflammatory cytokines (e.g., interleukin [IL]-6, IL-1, and tumor necrosis factor alpha [TNFα]).

For example, perturbed regulation of murine 17β-HSD8 encoding a component of the mitochondrial FASII enzyme 3-oxoacyl-thioester reductase is implicated in polycystic kidney disease.

Development of OSCC involves perturbed regulation of genes functioning in interaction with the external environment, such as those functioning in cell adhesion and encoding components of the extra-cellular matrix (Figure 3a,e,f).

We will first show that the sampling conditions on accomplishing sampled-data perturbed consensus and perturbed output regulation separately.

Consequently, perturbed feedback regulation to increased sterol levels has become a pervasive concept in the prostate cancer setting.

Pathway analysis and model simulations led to the hypothesis that YP CO92 cannot utilize rhamnose and melibiose due to a missing sink reaction and perturbed gene regulation, respectively, but other possible mechanisms have been advanced.

This was quite different to the dwarfed SCW CesA transgenic lines and suggested that the brittle node phenotype may be a direct or indirect result of the perturbed co-regulation between eHvCesA8 and other eHvCesA genes.

These agents act via a mechanism that modulates the Ca2+-sensitivity of troponin; such a mode of action is therapeutically desirable because intracellular Ca2+ concentration is not perturbed, preserving the regulation of other Ca2+-based signaling pathways.

Signature analysis suggested potential safety risks of perturbed blood pressure regulation and phospholipidosis, but ancillary data were not available to confirm these findings.

In acute and subchronic animal studies, perchlorate administered through the oral route (0.01 30 mg/kg/day) reduced uptake of iodide into the thyroid, perturbed thyroid hormone regulation, induced hypertrophy and hyperplasia in thyroid cells, and caused an increase in thyroid weight (Argus Research Laboratories 1998, 2001; Caldwell et al. 1995; Springborn Laboratories 1998; Yu et al. 2000).