Sentence examples for perturb the sequence from inspiring English sources

These structural changes perturb the sequence of genes along chromosomes.

Notwithstanding, it allows to study phenotypes without the problematic issue of genomic random integration, which may perturb the sequence of relevant genes as those implicated in processes regulating pluripotency/differentiation/metabolism.

Efficient removal of reaction by-products, which could otherwise perturb the sequencing reaction, is facilitated by the laminar flow.

In addition, the enrichment of cis-SNPs is not limited to the highly conserved sequences between mouse and human, and in fact in a majority of the CEGs the cis-SNPs do not overlap any conserved sequences in the promoter or non-coding regions, suggesting that the cis-SNPs in these genes do not perturb the highly conserved sequences in the immediate vicinity.

Randomisation of syllables perturbs the natural sequence of syllables, but preserves the natural order of the joint spectro-temporal modulations within a single syllable.

Fourth, genetic, biochemical and biophysical approaches will be developed to measure and perturb the roles of DNA sequences and trans-acting factors (proteins, RNA) in the formation of local and global aspects of the 4D nucleome and their impact on transcription and other nuclear functions.

Furthermore, perturbing the DNA sequences themselves may obscure relationships or even lead to false associations [ 71].

The inability to directly test and perturb the regulatory activity of large numbers of DNA sequences has hindered efforts to discover how cis-regulatory function is encoded in genomic sequence.

W7F is a conservative mutation, found in many myoglobin sequences; this mutation does not perturb the secondary or tertiary structure of apomyoglobin.

The equivalent nucleotides in bacterial 16S rRNA form part of the decoding sequence where aminoglycoside antibiotics bind to perturb the accuracy of protein synthesis (Fig. 1) (11).

Some alter methylation, while others perturb the histone-modification system.