LY294002, a PI3 kinase inhibitor, exerts its anti-angiogenic effect in a dose-dependent manner, without perturbing existing vessels.
This new semantic component is orthogonal to the syntactic metadata, so it does not perturb the existing design.
The project applies these climate data to perturb an existing 72-year historical hydrologic time series of the San Joaquin Basin to develop an integrated impacts analysis of climate change/variability on the water, economic and social resources of the Basin.
These currents can induce the magnetic field and perturb the existing field lines and these currents were found to depend on the direction of the interplanetary magnetic field direction.
However, as noted by Michael Lai, a virus expert, "When we expose ourselves to exotic animals, there is always a risk of being exposed to something unknown…When we perturb the existing peace between human beings and nature, we are opening a Pandora's box, which may contain surprises" (40 ).
There are several ways of perturbing the existing state of the attractor.
By perturbing naturally existing bistable switches, many environmental chemicals are likely to produce threshold responses through saddle-node bifurcations.
For example, if intragenic DNA methylation mediates the generation of many splice variants from the same gene, this may enable a methylated gene to take on new functions without perturbing the existing isoforms.
The performances of the proposed ATAMPPT have been compared with that of three existing MPPTs namely Perturb and Observe (P&O) and an adaptive P&O MPPT.
Additionally, single nucleotide polymorphisms (SNPs) in the 3′UTR of genes are recognized for their ability to perturb miRNA binding by modulating existing MREs or by creating new MREs [22 25].
