For MMA, our results corroborate observations from three other pertinent trials [ 17, 32] and one equivalent trial comparing oral to parenteral administration [ 12].
Most respondents also felt that they did not have access to pertinent clinical trial information; 68.8% indicated a score of ≤3 regarding access to clinical trial information.
Pertinent clinical trial problems were identified and solutions sought.
These statistics arise as score tests in logistic regression of active (1) versus placebo or usual diet (0) randomization assignment on the number of minor SNP alleles with logistic regression location parameter offset by log q/(1 - q), where q is the fraction of women assigned to active intervention for the pertinent clinical trial component.
Various stem cell therapies have shown promise, and pertinent clinical trials are summarized in Table 2. Stem cell transplantation can provide systemic improvement to the wound site, including enhancement in cell proliferation, ECM synthesis, growth factor release, and neovascularization.
We searched MEDLINE, the Cochrane Library, all retrieved trials and pertinent reviews for trials published between 1981 and September 2002.
However, initial results from another EUROPA subanalysis [ PERindopril, Thrombosis, InflammatioN, Endothelial dysfunction and Neurohormonal activation Trial (PERTINENT)] (Scientific Committee of the PERTINENT substudy, EUROPA-PERTINENT subcommittee 2003) provide indirect evidence that perindopril treatment does improve endothelial function.
Under this hypothesis, working memory stores information that is pertinent to one trial only (for instance, which arms have already been visited), but which has to be erased before the next trial to allow correct performance.
The ultimate objectives of the review are to encourage decision making in the field to move away from the automated/non-automated dichotomy and to develop criteria pertinent to each trial against which all available procedures are evaluated.
The generalisability of our findings may be limited since we studied trials with event rates that are pertinent to radiotherapy trials in patients with early stage breast cancer.
