Sentence examples for pertinent targets from inspiring English sources

Current therapeutic approaches are accounting for FcRs as pertinent targets for the treatment of inflammatory diseases (Hogarth & Pietersz, 2012).

Indeed, as it is well accepted that miRNAs control functional organized networks, it is tempting to speculate that the nodes or hubs of important regulatory pathways targeted by the miRNAs might constitute pertinent targets for therapeutic intervention.

This study pursued the role of the NF-κB pathway in the regulation of chondrocyte death induced by tumor necrosis factor alpha (TNF-α) and the pertinent target molecules involved.

This finding offers a rationale for pharmacological intervention in the treatment of cartilage repair in osteoarthritis and potentially of other joint-related diseases and shows that IGFBPs are pertinent target candidates for this purpose.

It allows a rapid characterization of the most pertinent mRNA targets according to several existing miRNA target prediction approaches.

KLF4 differentially regulates pertinent endothelial targets and important regulators of vascular homeostasis and atherothrombosis [ 16].

Here we illustrate the main steps of tumor angiogenesis process, defining the pertinent therapeutic targets and the efficacy and toxicity profiles of these new promising agents.

The definition of pertinent treatment targets for SpA is challenging because of the heterogeneity of the disease, including axial, peripheral and extra-articular/extraspinal manifestations.

This is particularly pertinent when targeting sparse police resources in time and space.

The growing importance of understanding the evolution and role of ice giants in extra-solar planetary systems makes Uranus a pertinent scientific target.

The assay involves combining toxin with antibody and incubating the mix over the neuroblastoma monolayer for several days, after which, the cleavage of the pertinent SNARE target is monitored.