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It is pertinent to mention here that replacement of A G with C C involves a substitution of a purine purine base pair by a pyrimidine pyrimidine base pair in variant 1.
More pertinent, our findings suggest that the replacement of a hydrophilic serine by a hydrophobic isoleucine may alter the flexibility as well as the surface architecture of the CARD 2 domain, in particular the exposure of hydrophobic areas.
As the role of mental health in outcomes studies after joint replacement becomes increasingly elucidated, it seems pertinent that mental health should be regarded as a comorbidity and accounted for in a comorbidity index.
The latter is especially pertinent given that the premature termination of the HABITS (Hormonal Replacement Therapy After Breast Cancer – Is It Safe?) trial [ 77] may lead to increased phyto-oestrogen use.
This manuscript reviews recent data pertaining to the use of renal replacement therapy, with an emphasis on those aspects of dialysis management that are especially pertinent to pediatric ESRD and acute kidney injury care.
In light of the versatility of kirmes, it would seem pertinent to reinvestigate the performance on a wider selection of data, e.g. by choosing priority as a replacement for the older sampling program or the simplistic oligo-counting method.
Hardly pertinent?
This seems pertinent.
These recommendations are pertinent.
Consider a pertinent example.
What is pertinent?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com