Sentence examples for pertinent changes in from inspiring English sources

A comprehensive understanding of the pertinent changes in the epigenetic makeup of suicide phenotype exhibits a characteristic signature with the possibility of using it as a biomarker to help predict the risk factors associated with suicide.

They may reflect the character of pertinent changes in various vital functions, influencing the general state of the organism.

Expression of c-Fos in brain regions known to respond to immune stimulation (Frenois et al., 2007) was used to examine whether the exaggerated sickness response to MDP + LPS (0.83 mg/kg) is reflected by pertinent changes of neuronal activity in the brain.

With the precise knowledge of the most pertinent ontogenic changes in TLR responses in hand, we are now well positioned to initiate a targeted interrogation of the underlying molecular mechanisms governing early life innate immune ontogeny.

Which dietary modifications should be undertaken in order to bring a pertinent change to the lipidome with respect to the risk of breast cancer is currently unknown.

The development of polymer-based computer-aided design and computer-aided manufacturing (CAD-CAM) milling bocks and the limited availability of independent studies on these materials make it pertinent to evaluate changes in their mechanical properties after simulated aging to identify strengths and limitations.

Although changes at the mRNA level are indicative of functional changes, it is more pertinent to study changes in the expression of proteins.

In this review, we discuss the pertinent literature regarding phenotypic changes in mice bearing inactivation mutations of 5-HT receptors, 5-HT transporter, monoamine oxidase A and other components of the serotonergic pathway.

This was accompanied by serial muscle biopsies to measure time course changes in pertinent GH and insulin signaling proteins.

It is pertinent to acknowledge that changes in gene transcription do not necessarily translate to changes in protein abundance and functional activity due to post-transcriptional regulatory mechanisms.

Particularly pertinent for IBD, methylation changes in SFRP2, measured in fecal DNA samples, have been used to identify patients with colorectal cancer with approximately 75% sensitivity and specificity.