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A personalized reference sequence database generated by the high-throughput sequencing pipeline is used to interpret antibody-derived peptide mass spectra obtained through the proteomics pipeline.
In particular, VERSE customizes both virus and host reference genomes to create personalized reference genomes, to which short reads align more easily.
Incorporating genomic information into allelic ratio measurements, for example by normalizing allelic RNA expression ratios to matched DNA ratios or by constructing personalized reference genomes for mapping, greatly improves allelic RNA ratio estimates [ 14, 26, 27].
The personalized reference to patients as " my patient" was evidence of a period of growth from students feeling like " guinea pigs" to " teachable learners" who accept the responsibility that embodies the profession [ 12].
With the ability to generate a personalized reference database, it is now possible to apply shotgun-style MS proteomics to the analysis of serum antibodies, as demonstrated by recent studies identifying antigen-specific monoclonal antibodies directly from serum, yet even with the availability of such a database, confident identification of monoclonal antibodies is not trivial.
This personalized reference will have an impact, as it leaves the impression that you have connected enough with them to want to be in their presence again.
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Included are personalized address labels.
Therefore, it is rational to use this method to obtain other personalized anatomical reference atlases to perform cerebral cortex or subcortical structure morphometry or volumetry analyses.
IMR/DENOM alone was chosen for comparison because other reference-guided assembly methods produce contigs or are generally designed for creating new reference sequences rather than "personalizing" existing reference sequences, which is the purpose of SHEAR.
The rapid genetic changes of the virus sequences require customized (or personalized) virus references that can take into account virus polymorphisms and evolution.
Make sure that each message is personalized and accurately references actual contributions made by the person being welcomed.
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