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Under the personalised strategy, 53% of men would be eligible for screening with 93 of cases being screen detectable.
Under the personalised strategy, 50% of women would be eligible for screening with 73 of cases being potentially screen detectable.
Exciting developments in the molecular sciences and the multi-platform high-throughput methods increasingly applied to diverse tumour types are slowly revolutionising established treatment approaches, and raise hopes of a more personalised strategy in the future treatment of CPM.
By studying the psychometric properties of PGOM's in this population and exploring what patients think and feel about using them, we will be able to generate, in an international and multidisciplinary platform, a guidance document that will help clinicians and researchers taking this personalised strategy on board.
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This includes developing personalised strategies for the rapid correction of setbacks.
An important area of current research aims at defining biologically personalised treatment strategies through the identification of new predictive and prognostic biomarkers that provide guidance in the choice of the therapeutic strategy.
In view of our current limitations, to understand asthma and design personalised treatment strategies for each patient, requires thinking of systems medicine.
The findings support the development of a definitive trial that embraces personalised recruitment strategies and the development of approaches to improve retention over a clinically relevant intervention period.
This could be conducted at the time of diagnosis and therefore, be used to facilitate personalised treatment strategies, as well as enabling identification of those relatives who have also inherited a similar high breast cancer risk.
More studies are urgently required to test the clinical utility of using CTCs as a liquid biopsy to monitor tumour genotypes and to contribute to personalised treatment strategies in GI cancer.
Therefore, we recommend future research to explore the position of this biomarker in the clinical management of OSCC and to evaluate whether it can contribute to personalised treatment strategies.
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