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"One can foresee the further expansion of PET imaging based personalised management of cancer, which, based on the strong evidence generated through a number of clinical studies and by its ability to monitor disease activity at the individual level, is likely to be increasingly integrated into the standard evidence-based clinical practice of oncology" [22].
It would be helpful to understand why GPs altered personalised management plans in some patients when there were no indications that side effects or other drug-associated problems increased.
Guidelines for the advice of further actions to be suggested in the presence of potentially clinically relevant IF may be more difficult to set up; the adoption of multidisciplinary clinico-radiological approaches could enhance the clinical efficacy with a patient-centred and personalised management [20].
This may assist in the development of personalised management strategies.
The proposed system may reduce the referral rate for colposcopy and guide personalised management and therapeutic interventions.
Development of predictive biomarkers that differentiate benefit from different local treatments and active surveillance would further enhance personalised management of early prostate cancer.
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Data from continuing clinical and translational research are urgently needed to improve, and, crucially, to personalise management.
This personalised cancer management strategy may reduce treatment-related toxicities and ultimately improve patient outcomes.
For the UPBEAT-UK qualitative study, reported on here, the aim was to explore patients' own experiences, priorities and meaning making to inform the design of a nurse led personalised, case management intervention.
Using the profiles to provide personalised self-management support may positively influence the effectiveness of the support and self-management interventions.
In addition, personalised self-management plans could be modified or updated remotely according to patients' needs.
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