Reactions to the news of Thatcher's death were mixed in the UK, ranging from tributes lauding her as Britain's greatest-ever peacetime Prime Minister to public celebrations of her death and expressions of personalised vitriol.
Prospective studies are needed to further validate the potential roles of MMSET and UBC9 on BRCA1 expression-based personalised therapeutic strategy in gastric cancer patients.
Possible applications of these biosensors range from diagnosis of genetic diseases [ 1], detection of infectious agents [ 2], study of genetic predisposition [ 3], development of a personalised medicine, detection of differential genetic expression, forensic science [ 4], drug screening [ 5], food safety [ 6], or even environmental monitoring [ 7].
In future, analysis of the patients' tumour cells' β-tubulin isotype expression pattern may assist in making personalised therapy decisions in certain cancer types.
Dubbed ReactivAds, the new suite of interactive video ad formats promises to leverage "emotion, facial and gesture recognition" via any device's webcam to offer a much more personalised ad experience based on Vyking's live facial expression analysis technology.
Recently, the introduction of microarray-based gene expression refreshed the prospects for more accurate personalised approaches (Sotiriou et al, 2003; Roukos et al, 2007).
Current state-of-the-art approaches that take into consideration oestrogen receptor (ER), progesterone receptor and HER-2 expression in primary tumours advanced, albeit modestly, personalised breast cancer therapy.
Participants expressed a strong preference for personalised quit support.
"Patients are likely to find it more meaningful if you offer a personalised apology – for example 'I am sorry …' – rather than a general expression of regret about the incident on the organisation's behalf," says the guidance, which was prompted by the Mid Staffordshire care scandal.
Therefore, biclusters which are determined from multiple and potentially overlapping gene expression profiles may be more relevant in the context of personalised medicine, which requires finer groupings of patients with specific molecular and clinical characteristics.
