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Inter-individual differences in 3′end architecture and, therefore, in the regulation of 3′end processing, have been found to cause the observed changes in mRNA polyadenylation and cleavage between individuals, contributing to "personal" gene expression profiles.
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She is interested in applications to personal genomics, genetics of gene expression, and gene networks in disease, leveraging diverse data to infer more comprehensive models of genetic effects on the cell.
Certainly, having both personal genomes and longitudinal gene expression profiles from the same study participants has clear advantages.
Since the action of positive selection can now be inferred solely from cis-eQTL (H. Fraser; personal communication), selection on gene expression can be measured by NSR/RNA-seq in a wide range of species.
Gene expression was normalized against expression of the GhEF1α gene.
Using TIGR's pseudomolecules and publicly available rice EST sequence data, Affymetrix has recently constructed a rice gene expression array with 46,115 rice gene models (Affymetrix, personal communication).
My personal view is that all toxicity pathways revolve around stress responses and the control of gene expression".
While promoters provide temporal and spatial control of gene expression, FPs do not always require a promoter for expression (A. Fire, personal communication).
Considering gene expression consistency (the number of single cells in which a gene was expressed), gbM genes had a significantly higher gene expression consistency than unmethylated genes.
Gene expression.
This suppresses gene expression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com