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The gene is persistently mutated in eight series, (three of which were driver mutations), followed by ten genes mutated in seven series.
To determine the probability of observing x recurrent, persistently mutated ORFs outside of LOH regions, we developed an additional stochastic simulation model.
Likewise HYR3, a known virulence gene, was persistently mutated in nine of the patients, three of which occurred in LOH tracts, including one in which a new allele was homozygosed.
"It's mutating constantly.
They're mutating.
"They're mutating!" Xander gasps.
"They're mutating!" he gasped.
In addition, the external environment keeps mutating.
Is it bionically mutating my food?
Pancreas tumors are complex and continually mutating.
Genes mutate rarely; memes mutate rapidly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com