The one exception was a patient with normocalcemic PHPT, in whom persistence was defined as persistently increased parathyroid hormone levels postoperatively.
However, if a 'chronic inflammatory configuration' persists, as in autoimmunity, the effects are detrimental because of the persistently increased SNS activity, HPA activity, and the resultant chronic catabolic state.
White matter abnormalities may play a role in the persistently increased risk for bipolar disorder following childhood trauma.
The saturation magnetization of the CoxFeyBz coatings persistently increased as the heat treatment proceeded or as the temperature elevated, which contributes to the improvement of permeability.
Conclusion: Endothelin levels after CPB remained persistently increased for at least 24 hours after surgery and were associated with increased myocardial production of endothelin.
Where DSM-IV required, as criterion A, the presence of one of the two mood symptoms (elation/euphoric or irritable mood), in DSM-5, 'the mood change must be accompanied by persistently increased activity or energy levels'.
Bipolar disorder (BD) refers to a group of conditions that share the defining features of elated/euphoric or irritable mood accompanied by persistently increased activity or energy levels, also known as mania (American Psychiatric Association 2013).
Western blot analysis showed that CCI rapidly and persistently increased PKM2 expression in SC compared with naïve rats (P < 0.05), starting at day 3, peaking at day 7 and maintaining until day 21 (Fig. 1c, d).
While in the past only a distinct period of abnormally and persistently elevated, expansive or irritable mood was necessary, these symptoms now have to be present in combination with persistently increased (goal-directed) activity or energy, most of the day, nearly every day.
Persistently increased MMP activity within glomeruli may, therefore, be a result of an inflammatory process maintained by retained necrotic cellular debris linked to loss of apoptosis- and necrosis-related Dnase1 enzyme activity [38], [39].
Several recent studies in rodent models for NEC have implicated a persistently increased TLR expression on immature enterocytes and excessive NFκB signal transduction as the basis for inflammatory necrosis [17] [19], [22], [23].
