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More recently, it has been demonstrated that a chimeric BCL-xL protein containing helix α5 of BAX is converted into a proapoptotic factor [49]. Being the focus of the activity of these proteins so persistently directed toward the α5 α6 hairpin, the use of minimal systems, consisting of singular helix fragments, may help clarifying the molecular mechanisms of the full-length proteins.
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Nixon personally directed and persistently harangued his staff to audit, investigate and gather dirt on his enemies for personal purposes.
First, in a democracy, the Constitution directed the Court to insure equal rights for minority groups who might persistently lose out in the political process, with African-Americans being the paradigm case.
Therefore, in the present study, we used 5 polyclonal antibodies directed against differentially regulated chlamydial proteins during in vitro persistence [ 18, 19] to validate the use of TMA technology on non-persistently, persistently infected and uninfected HEp-2 cell pellets.
Alternatively, efforts could be directed toward developing population management programs that reduce ED use among those with diabetes, heart disease, and other co-morbidities that are associated with persistently severe ED patterns.
Circulating antibodies directed against podocyte cytoplasmic antigens (aldose reductase, SOD2, α-enolase) or against thrombospondin type-1 domain-containing 7A could define subsets of patients with positive anti-PLA2R or persistently negative anti-PLA2R, respectively, and perhaps with a different response to therapy [ 32, 33].
They found that in a homogeneous environment without haptotactic and chemotactic gradients to direct cell migration, the tumour morphology is persistently radially symmetric.
Speaking to Giant Spacekat studio co-founder Brianna Wu recently, I asked if there could be a silver lining to GamerGate, that by receiving abuse (Wu has been one of the most persistently targeted women across this "consumer revolt") she's actually benefitted, as her elevated profile will direct more attention the way of her team's work.
Wittman directs.
Sandberg directs.
Sister directs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com