It is possible that rigid sections of the nucleoid are less susceptible to phage integration, and chromosomes with persistent sequence periodicity are (partially) protected from phage integration.
Moreover, chromosomes that contain prophages tend to have weaker or less persistent sequence periodicity, suggesting that the periodicity and concomitant DNA curvature could also play a role in protecting the chromosome from phage integration.
Integrated prophages can comprise up to 10 20% of the chromosome size [ 25], and additions of such an amount of non-periodic DNA into a chromosome with otherwise persistent sequence periodicity could decrease the values of the Max2, Max3, and MaxMax indices.
If hi is true, then for a persistent enough sequence of observations (i.e., if proper detectors can be built and trillions of protons kept under observation for long enough), eventually a proton decay will almost surely be detected.
Su var)3-9 proteins contain only four persistent conserved sequence differences to these paralogous proteins: G450 (Fig. 7, position 450 according to D. melanogaster Su var)3-9) in preSET, G487 in SET-N, YddqGrT (positions 524 to 530) in SET-I, and H557 in SET-C.
It is noteworthy, for example, that three of the groups in which apparently persistent coding sequence heteroplasmy is documented in wild taxa- Hawaiian Hylaeus, Indonesian Chitaura grasshoppers [ 29], and Mauritian Drosophila [ 66]- are island endemic species, where adaptive radiation and/or low population sizes may result in increased rates of change [ 39].
Cutadapt 1.0 [ 38] was used to remove these persistent adapter sequences and to remove nucleotides with low quality scores (phred < 20).
However, despite persistent declines in sequencing costs, population-based rare variant detection across large genomic target regions remains cost prohibitive for most investigators.
Our goal is then to compute persistent homology for a sequence of nested spaces (S_{epsilon_{1}},S_{epsilon _{2}},dots, S_{epsilon_{l}}), where each space gives a 'thickening' of S in X.
In the presence of thrombin, the quadruplex is stabilized, leading to more persistent presentation of a sequence that can then interact with a toehold on H2.
Analyses of prokaryotic gene repertoires revealed a persistent bias of disruptive sequence repeats towards gene termini, potentially to curtail the metabolic costs or toxicity associated with transcribing and (or) translating non-functional genes [ 13].
