Sentence examples for persistent reservoirs of from inspiring English sources

Therefore, current anti-HIV-1 research efforts are increasingly focused on strategies aimed at reducing the size of these persistent reservoirs of latent HIV-1 by forcing viral gene expression.

Kandahar and Helmand have long been identified as the epicentres of polio in Afghanistan and the Southern Region as one of the most persistent reservoirs of poliovirus globally.

The achievement is especially significant because Kandahar and Helmand provinces have long been identified as the epicentres of polio in Afghanistan, and the Southern Region as a whole one of the most persistent reservoirs of poliovirus globally.

Since first described nearly two decades ago a persistent reservoir of HIV-1-infected cells remains the main reason that HIV-1 infection cannot be cured (Chun et al., 1997; Finzi et al., 1997; Wong et al., 1997).

The high incidence of TB in prisons contributes to a high rate of TB transmission among inmates, who serve as a persistent reservoir for spillover TB transmission into the general population [ 6, 7].

Thus, this enables the use of the resource for current important topics such as studies of eradication of HIV from persistent reservoirs, aging with HIV, and pathogenic mechanisms of HAND in the setting of long-term treatment.

Persistent reservoirs remain the major obstacles to achieve an HIV-1 cure.

On the other hand, viral reservoirs could provide a persistent source of recrudescent viraemia despite temporary remission of HIV-1 infection after withdrawal of treatment [ 23], as observed in the so-called Mississippi baby [ 24].

WNS is contagious between bats, and mounting evidence suggests that a persistent environmental reservoir of Pd plays a significant role in transmission as well.

Clearance of HIV infection will almost certainly require a multimodal approach that includes potent suppression of HIV replication, therapies that reach all compartments of residual HIV expression, and depletion of any reservoirs of persistent, quiescent proviral infection.

In fact, Stewart et al. [ 68] have suggested that lung epithelial cells may be long-term reservoirs of persistent viral infection.