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Our results suggest that the persistent polarization underlying many cellular and developmental processes could arise through a simple biophysical process, without any additional biochemical feedback loops.
Thus the microtubule network is required for persistent polarization and optimal migration in T cells [10].
Despite this rapid turnover at the molecular level, the position of the actin caps remained stable over much longer time scales, typically exhibiting persistent polarization for hours.
This hypothesis was confirmed by the observation that acute application of a large hydrodynamic force to ECs resulted in an immediate downstream displacement of nuclei and was sufficient to induce persistent polarization.
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Transcranial direct current stimulation (tDCS) induces long-lasting NMDA receptor-dependent cortical plasticity via persistent subthreshold polarization of neuronal membranes.
On the other hand, chronic inflammation with persistent M1 macrophage polarization is associated with an increased risk of cancer development [4].
Enhanced microglial activation and persistent skewing toward M1-like polarization in the MPI118Q/118Q cerebellum may be associated with PC loss because persistence of an inflammatory stimulus can result in neurodegenerative pathology (27).
It lay in the redemptive solidarity displayed — below ground, by rescuers at the site and on a global level — at a time of shrieking polarization in the United States, rampant self-obsession and persistent division.
Using orthogonal polarization spectral imaging, Top and colleagues demonstrated in septic children that persistent microcirculatory alterations were the single most sensitive and specific indicator of outcome [ 34].
Yet Trump's more persistent appeals to a lingering sense of grievance, combined with resentment from Democrats amid a period of polarization, has helped him secure an ignominious distinction.
These leaders seek to redress persistent poverty, income inequality, weak institutions and rampant crime -- the real reasons behind the region's political polarization and its penchant for populism -- amid fierce pressures from both global markets and democratic electorates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com