Finally, we asked whether the persistent, out-of-target Y autophosphorylation of HIPK2Y354F takes place in cis or in trans.
The gap in healthcare coverage results in a persistent out-of-pocket expense for every patient, potentially leading to decreased medication adherence that may reduce treatment effectiveness, as has been demonstrated by Fung et al. in patients with diabetes [ 30].
Besides persistent stock-outs, fears of side effects, and religious and cultural factors, family planning uptake is also held back by a "weak health system with the perennial challenges of inadequate and less motivated human resources for health", argues Mugirwa.
If compared to the measurements of the C. alatus that had died earlier, those that produced persistent, dried-out stems (i.e., 0.8±0.04 cm in diameter) were, based on this curve, among the tallest individuals (see also Fig. 4B).
Because the C. alatus genes are expressed beyond their immediate boundaries through these persistent dried-out stems, one can consider that this example corresponds to an "extended phenotype" [43] rather than "niche construction" which implies that genes are not involved in the legacy [44] (see also the controversy on this subject in [45]).
This is most likely explained by frequent and persistent stock-outs of HIV test kits during the study time-frame [ 19, 23].
Whereas the government of Uganda has recently embarked on expanding health infrastructure and increasing the presence of health workers in rural areas in a bid to address the quality issues, persistent stock-outs of essential medicines, supplies and absence of medical equipment is still apparent [ 36].
(Pity that at the matinee caught, a persistent helicopter drowned out much of the denouement).
Others send out persistent e-mail appeals to high school sophomores, with breathless subject lines like "Time is running out".
The case, which was heard last year, was the first in which GCHQ admitted to carrying out "persistent" hacking in the UK and overseas.
