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The cisplatin-resistant BGC823/DDP cells were developed from the parental BGC823 cells that were subjected to persistent gradient exposure to cisplatin for about 12 month, through increasing cisplatin concentration from 0.05 μg/ml until the cells acquired resistance to 1 μg/ml.
The cisplatin-resistant BGC823/DDP cells were developed from the parental BGC823 cells that were subjected to persistent gradient exposure to cisplatin for about 12 months, through increasing cisplatin concentration from 0.05 μg/ml until the cells acquired resistance to 1 μg/ml.
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There was a persistent socioeconomic gradient in 1-year survival in England and Wales for more than 3 decades (1971 2001).
6 8 There is a persistent socioeconomic gradient across CHD mortality in many countries, and in some places, inequalities may be widening.
We conclude that the persistent socioeconomic gradient in survival among women with ovarian cancer, at least for 1-year survival, may be due to differences in access to treatment and standards of care.
Previous studies reported a consistent association between the levels of periodontal disease and skin color among adults after adjustment for other socioeconomic variables [ 36], and a persistent color/race gradient in the prevalence of dental outcomes was observed among adolescents, with the darker the participants' color, the higher the prevalence of unfavorable oral health conditions [ 37].
The constructs were able to administer NGF release and to maintain persistent NGF gradients longitudinally distributed inside the PLGA/CH conduit for about 6 weeks or even longer.
Even if global measurements show that global characteristic times for mixing and mass transfer differ by two orders of magnitude, local experimental characterization shows persistent vertical gradients of dissolved gas concentrations.
The persistent social gradients in subjective oral health further highlight that health inequalities should be considered a public health priority.
But throughout this period infant mortality has shown marked and persistent socioeconomic gradients within countries, even in countries with universal healthcare access [ 2- 4].
Such persistent pressure gradients could be maintained by a poroelastic cytoplasm, where intracellular networks and other macromolecular structures interfere with rapid pressure equilibration [ 30].
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