Exact(7)
More importantly, these studies also demonstrated controlled, highly persistent generation of biologically active proteins targeted to structures deep in the human brain.
It is not known at present how the persistent generation of MPO-derived oxidants evokes adverse effects in vascular tissues.
Persistent generation of significant levels of ONOO- can lead to the induction of cell death, either apoptosis or necrosis.
This results because of persistent generation of hydroxyl radicals within the core due to the redox reaction between H2O2 and Fe2+ that has diffused into the core.
One possibility might be that they are influenced by the chronic state of the disease and the persistent generation of Aβ plaques (in AD) [ 22].
In contrast, skeletal muscle shows a persistent generation of autophagosomes that continues for days, suggesting that different mechanisms control autophagosome formation during short or long periods of induced autophagy.
Similar(53)
The factors that contribute to the pathogenesis of pulmonary fibrosis include persistent inflammation, generation of pro-inflammatory, pro-fibrotic and angiogenic mediators, alveolar epithelial cell injury, fibroblast differentiation, and poor apoptotic activity of the myofibroblasts.
Persistent expression and generation of infectious virus in renal cells required HIV integration.These results support the kidney as a potential reservoir where virus is exchanged between interstitial T cells and RTE cells.
We propose that endosulfan induces the activation of CYP1A in HK which led to the generation of persistent metabolite, ESS, resulting in immunotoxicity.
With a few exceptions, New York City's most sweeping political changes have come through court action, or after at least a generation of persistent political lobbying, not at the public's initiative.
After over a generation of persistent and acrimonious labor shutdowns, the United Steelworkers of America had not called an industrywide strike since 1959; the United Auto Workers had not shut down General Motors since1970.
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