But by 2010, Allison's persistent efforts to apply this approach to humans could no longer be ignored.
But a challenge this big requires persistent effort over a long period as well as the collective action of governments, multilateral organizations, civil society, and business.
The novel tool materials, which have passed the trials, are the products of the persistent effort of thousands of crafts-people, inventors, technologists and scientists, blacksmiths, engineers, metallurgists, and chemists.
This assumption is based on the general idea that high expectations may induce persistent effort to achieve a goal whereas low expectations may result in disengagement from desired goals (Austin and Vancouver 1996; Carver and Scheier 1998).
We will continue the painstaking and persistent effort to ensure the security of our country and Europe under difficult circumstances, insisting on complete identification of those arriving".
Of note, a number of patients were selected based on known KRAS status established by clinical broad-based institutional tumour genotyping efforts independent of this trial.
I want to mobilise my international and Bangladeshi friends to make stronger and more persistent efforts this time.
"Verizon's persistent efforts to protect copyright thieves on pirate peer-to-peer networks will not succeed".
And as climate change becomes ever more evident, despite the weirdly persistent efforts of many absurd deniers in this country, humanity's future grows more in doubt.
Great performers have been shown to believe that their persistent effort will lead to success; researchers call this self-efficacy.
We may not realize this goal in my lifetime, but persistent effort can roll back the possibility of catastrophe".
