Sentence examples for persistent differentiation from inspiring English sources
However, exposure of experimental animals or humans to the potent exogenous estrogen, diethylstilbestrol (DES), results in persistent differentiation effects.
In a recent study, allogeneic grafts elicited persistent differentiation of monocytes into mDCs expressing IL-12 and stimulated T-cell proliferation and IFN- γ production.
This observation implies that there is persistent differentiation in allele frequencies between different host species and that many ST-21 isolates represent lineages that have persisted within the same host species long enough to acquire a substantial number of alleles.
Second, we propose that the persistent differentiation of Ptf1a cKO acinar cells is promoted by interactions with neighboring Ptf1a WT cells, producing a phenomenon similar to the 'community effect' in embryonic development (Gurdon et al., 1993).
Decreased expression of HES1 is observed as neurogenesis proceeds and in case of persistent expression differentiation of neuronal cells are blocked in the CNS [104].
On the other hand, the phenotypes of our experimental populations bred in the laboratory seem to contradict a persistent ecophenotypic differentiation between dwarf and normal whitefish.
However, there was a persistent and "continuing differentiation" between the English and Cornish peoples during the Middle Ages, as evidenced by documents such as the 1173 charter of Truro which made explicit mention of both peoples as distinct.
It would therefore be helpful to evaluate the effect of TGF-β3 on persistent fibroblast-myofibroblast differentiation beyond the completion of VFM wound closure.
The persistent eco-morphological differentiation in body shape and LPJ morphology of the ten investigated natural populations and the gold and dark common garden siblings suggests that the color polymorphism has potentially direct, genetically determined, ecological consequences [ 32].
The mechanism of lateral inhibition amplifies these small differences, using them to bring about differential gene expression that leads to stable and persistent states of cell differentiation.
This indicates that persistent Notch signaling blocks differentiation of both ciliated and NE cells, and may even interfere with Clara cell differentiation while maintaining the SPNC cell-like population.
