Sentence examples for persistent depletion from inspiring English sources

As previously reported, a noncontingent "binge" high-dose treatment regimen (4 injections of 10 mg/kg MA administered every 2 hours) produced persistent depletion of cortical 5-HT and striatal DA.

All four untreated and four of the seven minocycline-treated animals had persistent depletion of CD8+ lymphocytes.

Interestingly, curcumin also synergized with HDAC inhibitors vorinostat and LBH589, via persistent depletion of Hsp90 client proteins EGFR, Raf-1, Akt, and survivin [ 283].

The time course of DHEAS exhibited a persistent depletion during follow up, whereas cortisol levels were increased at all time points.

Apparently the anticoagulation regimes do not result in a persistent depletion of LPL, since the initial peak value after tinzaparin injection remained unchanged throughout the 6 month study period.

133 In 22 of the 35 patients, persistent depletion of hematopoietic tissue and accumulation of MAT was observed at time points ranging from 6 months to 15 years after irradiation.

The chronic administration of MDMA has been well-characterized for causing long-term persistent depletions in brain 5-HT levels, most likely due to the neurotoxic action of MDMA to 5-HT-releasing neurons [ 7, 24].

No significant toxicity was observed even in patients who had persistent arginine depletion for 3 or more months.

Renal biopsy in these patients demonstrates juxtaglomerular hyperplasia, but this finding is non-specific, probably secondary to persistent sodium depletion and hyperreninnemia [ 6].

Again, if a parallel is made with the condition of shock, severe and persistent mitochondria depletion may be a marker of an irreversible path toward death, possibly by multi-organ dysfunction syndrome.

To deplete NPC2 in H460 cells, we constructed shRNA for NPC2, and our selected clone showed persistent and profound depletion of NPC2 protein (Figure 3).