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However, upon differentiation of engrafted MSCs in vivo, they may acquire immunogenicity and could be eliminated by the immune system of the recipient [ 25], questioning the persistent benefit in the long run.
With continued treatment, patients initially randomised to abatacept experienced persistent benefit in synovitis and osteitis, with inhibition of erosion progression; patients initially randomised to placebo achieved incremental reductions in MRI assessed inflammation and slowing of erosion progression after switching to abatacept.
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Rather than simply improving outcomes in the short run, developing effective policies to assist cohorts of workers entering the labor market in an economic downturn may have important and persistent benefits in terms of wages and other non-monetary forms of compensation (e.g., health insurance).
These data demonstrate a disease-modifying persistent benefit for saracatinib in a preclinincal Alzheimer's model, and distinguish its action from that of memantine.
We report a persistent benefit of telemedicine, particularly in Hispanics, the group with the worst glycemic control and the lowest income, educational attainment, and computer experience.
Moreover, data showing a persistent benefit on preserving renal function is lacking, and it is these gaps in our knowledge that the ERICCIN trial aims to bridge.
These compelling longitudinal findings converge with other studies showing a similar pattern: The ability to resist temptation early in life translates to persistent benefits across settings.
Because of the scarcity of such cases, a randomized study to evaluate rFVIIa benefit in patients with persistent bleeding under ECMO is excluded.
This is an important clinical benefit in view of the persistent risk of relapse beyond 10 years in patients with HR+ tumors [ 4].
In contrast, therapeutic zinc supplementation during acute diarrhea has been reported to have a clear benefit in reducing the incidence of persistent diarrhea by ~25% and in reducing the proportion of children with persistent diarrhea > 3 days by ~30%[ 74].
But the Kurds' history with the state of Iraq is one of persistent enmity and bloodshed, and they see little benefit in joining up with their old antagonists.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com