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Animals lacking Pycard and Nlrp3 have similar levels of bacteria in the lungs during the growth and persistence phases of Mtb infection compared to wild type (Figure 3D, G).
At the booster and persistence phases the mean age of the infants was 12.5 months (11.9-13.6) and 24.1 months (22.1-27.3), respectively.
The contrasting evidence based on different murine models of arthritis suggests that endogenous GCs might play different roles during the onset and persistence phases of RA.
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In this system however, although phages were allowed to burst kill and persist in the environment, the persistence phase in harsh conditions was a separate experimental step from the replication in E. coli, potentially eliminating the possibility for alternative strategies to evolve and compete [ 39].
IL-1β levels increased during the logarithmic growth phase of infection and were still high during the persistence phase of infection (Figure 4A).
Hypoxia is one of the environmental signals that triggers mycobacteria to enter into a non-replicating persistence phase.
This phase IIb, open, randomized, controlled study conducted in the Philippines and Saudi Arabia consisted of a vaccination phase and a long-term persistence phase.
The study consisted of two phases: the vaccination phase (www.clinicaltrials.gov, NCT00356369) and the long-term persistence phase (up to 5 years after vaccination).
Out of the 509 infants enrolled in the study, 497 completed the primary immunisation phase, 478 the booster phase, and 453 the persistence phase (fig 1).
In granulomatous lesions, mycobacteria are exposed to hypoxia which triggers a hypometabolic state leading to a non-replicative persistence phase (Gengenbacher & Kaufmann, 2012).
The study was divided into three phases: the primary vaccination phase (from 2-5 mofths of age); the booster phase (from 12-13 mofths of age), and the persistence phase (at 24 months of age).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com