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ReA is the persistence of pathogenic organisms or its products in the joint/synovium leading to local immune response.
The proposed mechanisms for the generation of ReA is the persistence of pathogenic organisms or its products in the joint/synovium leading to local immune response [22].
This is likely to be significant as social traits are thought to be important in determining both the virulence and persistence of pathogenic microbial infections [29], [30], [31].
The ecologic persistence of pathogenic viruses has been the focus of many studies (1 – 4 ).
Overall, 2CA induced dramatic disease attenuation, which did, however, require continued injections due to obvious persistence of pathogenic transgene expression.
Persistence of pathogenic bacteria needs to be better understood, as Campylobacter, Salmonella, Shigella, and shigatoxin-producing E. coli have been found on algae growing in surface waters (Ishii et al. 2006).
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While considerable attention has been given to OMPs of vertebrate pathogens, the role and evolution of OMPs in the establishment and persistence of both pathogenic and non-pathogenic microbial associations found in invertebrates remain largely unknown.
These differences could have consequences in the persistence and evolution of pathogenic bacteria, which merit further study to understand the role of nematodes in the health of ecosystems.
Although drug resistance is not a virulence factor, it may play a role in the selection, persistence and dissemination of pathogenic strains of V. cholerae which are difficult to eradicate.
The impact of artificial barriers such as biogas-advanced waste water and waste treatment plants onto the spreading and persistence of veterinary pharmaceuticals, pathogenic microorganisms and their resistances is partly not well known.
B. abortus gluP mutants have a reduced ability to persist in the spleens of mice [48], suggesting that the ability to utilize these carbon sources may be important for systemic persistence of the human pathogenic Brucella species.
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