On the occasion that the causal agents persist, sustained inflammation is the result, together with connective tissue remodeling, where collagenases, such as matrix metalloproteinase (also transcriptionally driven by pro-inflammatory cytokines) play an active role (Mahé et al 2000).
Although the expanding tumor cell population may be successfully targeted, drug-resistant cells may persist and sustain the tumor or enter dormancy before igniting a future relapse.
Similarly, deletion of Fas in B cells causes autoimmunity, presumably because Fas-sensitive antigen-presenting B cells persist and sustain survival of self-reactive T cells that are usually deleted in a Fas-dependent manner.
Lower condom use with non-commercial relative to commercial partners persists and sustained interventions targeted toward increasing condom use within non-commercial partnerships should continue to be explored and developed.
In the rabbit endotoxin shock model, we reported that endothelial injuries and monocyte TF expression are sustained, persisting longer than five days after a single injection of lipopolysaccharide (LPS) [ 7- 12].
In contrast, when insulting agents persist over time, sustained cycles of cell proliferation and death in environments rich in inflammatory cells and their bioactive products may increase neoplastic risk and foster tumor progression [ 3].
The Antarctic population may be demonstrating the effects either of a founder event or bottleneck [ 63], where a founder effect may arise as a result of a number of opportunistic S. contortum individuals finding suitable conditions and settling at Hook Ridge, and persisting in the sustained diffuse hydrothermal flow at this site.
The peak titers for ELISA-binding antibodies and NAb were 1∶1024 and 1∶464, respectively; however, high ELISA-binding and NAb titers were not sustained and persisted for less than three weeks after immunizations.
But magical rather than spooky: animated by a conviction that the past persists and sustains the present.
Moreover, sustained oscillations persist when the PFL is removed, implying the crucial role of NFL for rhythm generation.
