Similar to observations with other bacterial strains, both invasive and non-invasive Shigella accumulated and persisted in the tumor after i.v. infection, whereas they were rapidly eliminated in the spleen (Fig. 2A, C).
Thus, we concluded that artificial box C/D RNAs effectively accumulated and persisted in human cells at least 72 h under the transfection conditions used.
We found an unanticipated amount of nonsynonymous variation accumulated or persisted in these genes in artiodactyl species during the short period of domestication (8000 – 10 000 years) and subsequent artificial selection.
Environ Health Perspect 123:1015–1021; http://dx.doi.org/10.1289/ehp.1409062 Persistent organic pollutants (POPs) are ubiquitous and persist in the environment, accumulate in high concentrations in fatty tissues, and are biomagnified through the food chain.
Their chemical, physical and toxicological properties vary greatly - while many are not hazardous or persistent, some are life-threatening on contact and some persist in the environment, accumulate in the food chain, travel large distances from where they are released, and are harmful to human health in small amounts.
For example, the accumulated mutations in an Escherichia coli clone that persisted in a family for 3 years gave a rate of 2.26 × 10−7 changes per site per year17.
Others persisted in new forms.
"Humans are exposed to triclosan transiently and in small doses, but the presence of triclosan in surface, ground and drinking water indicates its potential to persist and accumulate in the environment".
Since PCBs also persist and accumulate in the environment, the US Environmental Protection Agency EPAA) banned the manufacture of PCBs in 1977 and strictly regulates the storage, transport, and disposal of PCB materials [ 2].
Many of these chemicals persist in nature, so they accumulate in the environment.
They also tend to persist in the environment and accumulate in biological tissue.
