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The reluctance of surgical patients to participate may, in part, be a reflection of the significant decline in quality of life following surgery in the post-surgical period, and in particular symptoms that persist in the first 6-months post-surgery [ 53].
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If the study drug has symptomatic effects only, it would be expected that any differences between the two groups that developed in the first phase would not persist in the second phase.
And recent estimates show the declines persisted in the first half of this year.
And despite some strengthening of stock prices in the last couple of months, recent estimates show, the declines persisted in the first half of this year.
The slowdown appears to have persisted in the first three months of this year, when retail sales grew in real terms by just 0.3%.
The company said in a statement: "Operating conditions within the group's banking and advisory businesses remain mixed with low levels of economic activity and a difficult trading environment persisting in the first half of the financial year".
After adjustment for stage and comorbidities, the survival differential persisted in the first year but, when adjusted for treatment alone, this difference was no longer apparent.
"Weak market conditions for our industry persisted in the second quarter," the chief executive, Kurt Hellström, said.
Regarding the inventors, only 47 out of 199 (about 24%%) persisted in the second period from the previous one.
The Syrian community in New York preferred self-employment, and this practice persisted in the twentieth century.
Laden et al. (2006) recently extended the follow-up of the cohort until 1998, and confirmed that the association persisted in the second follow-up period.
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