ASM cells can contribute directly to the pathogenesis of asthma by expressing cell adhesion and co-stimulatory molecules and by secreting multiple proinflammatory cytokines and chemokines that may perpetuate airway inflammation and the development of airway remodeling in vivo [4].
In addition to their proliferative and contractile properties, studies suggest that ASM cells can contribute directly to the pathogenesis of asthma by expressing cell adhesion and costimulatory molecules and by secreting multiple proinflammatory cytokines and chemokines that may perpetuate airway inflammation and the development of airway remodeling in vivo[2].
As a result, this will perpetuate inequalities and hinder the development of culturally competent maternity services.
25 Thus, these disadvantaged children are less likely to become productive adults, 23 perpetuating the cycle of poor human development.
Malaria has serious economic impacts in Africa, slowing economic growth and development and perpetuating the vicious cycle of poverty.
Malaria also has serious economic impacts in Africa, slowing economic growth and development and perpetuating the vicious cycle of poverty – mainly afflicting the poor who live in malaria-prone rural areas.
His principal students, including his nephews Nicolas and Guillaume Coustou, perpetuated his influence, especially on the development of French portrait sculpture in the 18th century.
Excessive weight gain during pregnancy can increase the likelihood of further development of obesity, perpetuating the cycle of risk [ 11].
In summary, hypoxia may affect a host of genes that are involved in angiogenesis, apoptosis, cellular metabolism, matrix degradation and inflammation, thus perpetuating the cycle of reactions involved in RA development.
More help needed Prolonged interruption in school attendance impairs children's overall educational development, undermining the future employment opportunities and perpetuating the cycle of poverty.
