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Establishment of an epigenetic memory requires a mechanism to perpetuate marks during cell division in such a way that they can be inherited by the descendants within a cell lineage.
A striking example for an epigenetic role of replacement histones is that of CenpA, an H3 variant that has been shown to serve as a self-perpetuating mark on chromatin, important in the maintenance and reproduction of centromere chromatin regardless of its underlying DNA sequence (Cleveland et al., 2003; Bailey et al., 2013).
1– 7 From birth, the face is constantly exposed to sunlight, and so year by year, the skin will accumulate damage that gradually induces the appearance of visible signs of aging by marking areas of the skin, or perpetuating facial expressions.
Patronising and perpetuating myths again.
People think it's perpetuating neo-Nazis.
Who's perpetuating "Nixonland" now?
"You keep perpetuating the flow.
The media is perpetuating these views.
Florentino Pérez is perpetuating the tradition.
Ouch! Talk about perpetuating the gender stereotype.
He believes skyscrapers are worth perpetuating.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com