Sentence examples for perpetual activation from inspiring English sources

This class of drugs disrupts proper microtubule dynamics, leading to abnormal spindle formation, chromosome misalignment and the perpetual activation of SAC.

Due to the described mechanisms, these two drug groups represent a fairly logical choice for arterial antiaging, as the aging process is the consequence of their perpetual activation.

Finally, sustained proliferative signaling may well be the result of perpetual activation of the intracellular signaling chain independent of growth factors or receptors (e.g. mutated ras (257) or truncated src (258) are intermediaries of a normal proliferation signaling chain responsible for sustained proliferation).

In vitro EBV infection results in human B-lymphocytes activation and perpetual proliferation [32], [33].

These unique features, which are strictly dependent on NPM-ALK activity and expression, include perpetual cell growth, proliferation, and survival; activation of the key signal transduction pathways STAT3 and mTORC1; and expression of CD30 (the hallmark of anaplastic large-cell lymphoma) and of immunosuppressive cytokine IL-10 and cell-surface protein PD-L1/CD274 PD-L1/CD274

Epigenetic modifications lead to persistent activation of the protooncogene Ras, perpetual fibroblast proliferation and fibrogenesis [ 9].

Perpetual chronic inflammation results through a poorly understood milieu of cyclic cytokine cascades, activation, recruitment, proliferation and death, and driving atherogenesis.

In physiological kidney repair, reversible fibroblast activation is associated with reversible RASAL1 suppression without RASAL1 hypermethylation; whereas in pathological kidney fibrosis, perpetual fibroblast activation is associated with irreversible RASAL1 expression due to RASAL1 promoter hypermethylation (Bechtel et al., 2010).

Louisiana and Illinois were perpetual leaders.

Perpetual Groove, jamband.

Nothing is truly perpetual.