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The decision not to attempt to create all 5′ exon alternatives and all exon permutations was based on both biological and practical considerations.
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The generating process for these pseudorandom permutations is based on "logarithmic signatures" as described in [10 12] and uses a secret pass phrase as a key.
Permutations are based on 999 new data replicates.
The final permutation distribution was based on the cluster candidates of each permutation, with the highest sum of normalized difference.
The security of Birational Permutation scheme was based on the difficulty of solving the problem over (mathbb {Z}/Nmathbb {Z}).
This permutation test was based on a random background of 10,000 sets of annotations, shuffling the number of isoforms and the number of distinct isoform fitness profiles for each complex, which retains the distributions of those values.
The permutation analysis (see M&M) was based on 1000 permutations of gene-day signals across all 22000 genes at 5 days.
The declaration of statistically significant QTLs was based on permutation-derived empirical thresholds using 1000 permutations for each mapped trait.
An estimated false discovery rate (FDR) was based on permutations of the gene expression data as previously described [ 11].
LOD score was based on 500 permutations.
Statistical significance of pairwise FST values was based on 9,999 permutations.
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