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However, as such an approach would be best suited to LBC samples, the clinical and economic benefits of the various permutations of methods for obtaining and processing samples would need careful evaluation.
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To assess the utility of the many permutations of these methods, we compared phylogenetic trees made from CGH data to the MLSA tree for the sordariaceous fungi using both symmetric distance (SymD) and taxon pruning (D1).
These key structural and electrochemical properties of rGOs were found to be largely dependent on the permutation of reduction methods, in turn, affecting electrochemical properties.
We chose GSEAlm because it is a high-quality representative of permutation methods, and because it has more flexible options that most permutation software, being able to handle one-way ANOVA or block designs.
The result is a consistently derived database encompassing 64 permutations of FRP material, test method, and environmental conditioning.
SAM performs a moderated t-test on two user-selected groups of microarray datasets, and returns a set of discriminant genes ranked in descending order by d, the t-statistic, and calculates a false discovery rate (FDR) based on random permutations of the data labels (see Methods).
We compared the results obtained searching within human promoters with what we would expect by chance, by applying p53retriever to sets of scrambled sequences obtained by local permutations of real promoter sequences (see Methods and Additional file 3: Table S1).
In A and B, black outlines show p = 0.05 peak-level significance thresholds (empirical null distribution generated by 1000 random permutations of training category labels, see Methods for more details).
GeneSign proposes several types of permutation-based methods.
Yang and Churchill have noticed the problem of permutation-based methods when applied to small microarray experiments [ 8].
In this method, repeated permutations of the data are used to determine if the expression of any miRNA is significant related to the phenotype.
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