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Both chimeras are correctly targeted to the appropriate organelles, permitting deletion analysis to map protein subdomains critical for targeting.
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However, this strategy permits deletion of genes only during development of the parasite in the mosquito.
However, we have identified several defined genetic backgrounds that permit deletion of CDC13, but none of these permit deletion of STN1 or TEN1.
This approach permitted deletion of multiple genes within one strain without losing availability of auxotrophic markers.
We used Cre recombinase mouse strains to permit deletion of Lsd1 at early or later developmental stages.
Pif1 is a helicase that is active at telomeres and deletion of PIF1 and EXO1 also permits deletion of CDC13 (Dewar and Lydall, 2010).
LoxP sites flanking exon 2 of the AKAP5 locus were introduced to permit deletion of the entire open reading frame (Tunquist et al, 2008).
This replicative advantage mechanism suggests that the smaller deleted mtDNA molecules are replicated more quickly, permitting mtDNA deletion accumulation (10).
Similarly, because the law of double negation permits the deletion of a pair of consecutive negation signs, ∼(∃x) may be replaced by (∀x)∼, and ∼(∀x) by (∃x)∼.
It will be the first time an appellate court will rule on the constitutionality of a 3-year-old provision of the state Election Code that permits the deletion of a candidate's comments from the voter pamphlet "upon clear and convincing proof that the material in question is false (or) misleading..
The latter permits simultaneous deletion of β-catenin and EYFP marking, and is henceforth referred to as 'ABKO', for acinar-specific β-catenin knockout.
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