While sharing the strengths of a RCT, the efficient design also permitted us to use a smaller sample size versus a parallel trial, which is particularly suitable for rare diseases.
The research protocol was reviewed and approved by the Taiwan Ministry of Justice, which permitted us to collect blood samples from the participants.
These results also permitted us to stratify the samples into three different groups corresponding to European, African and Asian individuals, and to perform eQTL meta-analyses, which are more robust than conducting an eQTL analysis on all samples combined in regions of the genome where allele frequencies differ substantially between populations.
This method permitted us to select a representative sample of respondents from each of the three strata in equal proportions according to the total population in each stratum.
A perdeuterated aS sample permitted us to record very highly resolved 3D N N H NOESY spectra, yielding sequential dNN i, i+1) cross-peaks for the vast majority of residues, and observable dNN i, i+2) and dNN i, i+3) NOE cross-peaks for a significant fraction of residues in region I.
We found in an independent test session that the use of the MCT, an episodic memory test with no evidence of ceiling effects in our sample, permitted us to discover not only the interaction of amyloid with CR, but also the main effect of reduced performance with higher levels of amyloid.
Analysis of soil and water samples permitted us to assess the potential for off-site migration of antibiotics, and to identify environmental conditions that promote retention or on-site degradation of antibiotics.
Our large sample size permitted us to identify small effect sizes.
One of the major strengths of the current study was its large sample which permitted us to perform analyses for three separate age categories.
Because the rugged terrain of the LCR did not permit us to collect samples along a formal transect, we cannot unambiguously determine which specific biogeographic barriers maintain population isolation.
