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Expressing the C. elegans SID-2 gene in uptake-refractory organisms, including other nematodes, permitted uptake of ingested dsRNA [ 50, 52].
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The excretory cell expresses GTL-2 on its basal membrane, and this permits uptake of Mg2+ into the cytoplasm.
Possibly, renewed interest in this compound may be awakened by the introduction of a new device for delivering the drug by inhalation, permitting uptake through the vast and very thin barrier in the lungs.
Sensitization may occur as a result of reducing intra-tumoral pressure and lowering the macromolecular diffusion barrier, thus potentially permitting increased uptake of the immunocytokine antibodies.
Genetic competence, defined as a state that permits the uptake of exogenous DNA, is widespread among both gram-positive and gram-negative bacteria.
Two separate mechanisms exist for vitamin C uptake into cells: the high affinity, sodium-ascorbate cotransporters (SVCTs), 18 (also known as SLC23A1-2 (solute carrier family)) and glucose transporters (GLUTs), 19 (also known as SLC2A) the latter permitting the uptake of dehydroascorbate via facilitated diffusion.
Some transporters allow intracellular uptake of zinc, while others permit cellular efflux of zinc.
Use of Cy3 labeled dsRNAs permitted monitoring of the uptake of these molecules in tick tissues.
All exchange reactions were unconstrained permitting free uptake and secretion of respective metabolites.
In preclinical studies, quantitative assessment of tissue uptake permits better management of the therapy for an individual animal model and eventually enables assessment of overall response to a therapy in a population of transgenic animals [ 2].
Application of live confocal microscopy as well as quantitative flow cytometric assays permitted analysis of macropinocytosis by evaluating uptake dynamics of Alexa Fluor 647 in LNCaP cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com