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Those who discontinued treatment with all chemotherapy prior to disease progression continued treatment with sunitinib or bevacizumab as assigned at randomization (those receiving sunitinib were permitted to escalate the dose to 50 mg daily on schedule 4/2 at the investigator's discretion).
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5 Investigators were permitted to gradually escalate IFN-α from 3.0 to 9.0 MIU over a 3-week period.
Of note, afatinib-treated patients were permitted to dose-escalate from the initial 40 mg dose to 50 mg/day after the first 21-day treatment cycle if no drug-related AEs higher than grade 1 were experienced, while dose reductions in 10 mg decrements to a minimum final dose of 20 mg were recommended for patients experiencing drug-related grade 3 or selected prolonged grade 2 AEs [ 66, 67].
Or will they be permitted to step delicately around the escalating violence?
The system involves computerized parking meters that charge escalating rates in loading zones where trucks making deliveries or pickups had previously been permitted to park free.
China was not permitted to interfere.
I haven't been permitted to concentrate.
Junior monks are not permitted to read.
"I am not permitted to gamble".
Women are not permitted to drive.
Microfinance companies are already permitted to operate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com