The use of another biosimilar or a reference standard (e.g., human insulin for an insulin analog) as the reference product is not permitted by the majority of guidelines.
MR. SMITH -- The one thing, that I submit the court, the state should not be able to come in to say is: We are going to permit ourselves, the majority of people in our society, full and free rein to make these decisions for ourselves, but there's one minority of people [who] don't get that decision and the only reason we're going to give you is we want it that way.
Although the days are long gone when one female delegate was asked to leave an event because security assumed she must be a spouse without the required permit, the majority of the women in Davos are not there as participants.
Prompt treatment with corticosteroids or other immunosuppressive therapy, skipping a dose of ipilimumab, or in some cases discontinuation of ipilimumab therapy permitted resolution of the majority of severe events in a matter of days to weeks 22.
With the assayed amounts of tears utilized in the present work (mean 14±± 8 mL) it was permitted to detect the majority of molecules related to inflammation (as in the human cytokine panel utilized herein) in 92% of the samples.
Mitochondrial DNA present in the libraries permitted recovery of the majority of the mitochondrial genome sequence; assembly with the Newbler (proprietary: www.454.com) produced two large mitochondrial contigs from pooled 454 and Sanger sequence data (currently represented by Contig4281.1 and Contig4553.1 from the 2.1.8 assembly).
Indeed, it would be important to have a reliable non-invasive tool permitting to visualize the majority of pancreatic ductal carcinomas in patients.
Determination of SMN1 copy number in a general carrier screening population permits identification of the majority of SMA carriers before the birth of an affected child.
However, during the past five years, large scale sequencing approaches and microarray hybridization technology have permitted the localization of the majority of nucleosomes in the genomes of yeast, worms, flies and humans, and these genome-wide studies have revealed that a surprisingly large fraction of nucleosomes are well-ordered with respect to their positions along the chromosomes [3] [14].
This approach permitted the classification of the majority of subjects.
